Research Articles
Integron-Driven Antibiotic Resistance: How Gene Cassette Capture and Expression Fuel the Superbug Crisis
This article provides a comprehensive overview of integrons as critical drivers of multidrug resistance in bacterial pathogens.
Breaking Bacterial Resistance: Novel Strategies to Inhibit Plasmid Conjugation in MDR Pathogens
This review provides a comprehensive analysis of current strategies to inhibit horizontal gene transfer via conjugation in multidrug-resistant (MDR) bacteria.
Targeting the SOS Response: A Novel Strategy to Curb Antibiotic Resistance Gene Acquisition in Bacteria
This article provides a comprehensive analysis of the SOS response as a critical bacterial pathway facilitating horizontal acquisition of antibiotic resistance genes (ARGs).
Unearthing the Hidden Arsenal: A Guide to Identifying Novel Antibiotic Resistance Genes in the Environmental Resistome
The environmental resistome constitutes a vast, underexplored reservoir of antibiotic resistance genes (ARGs) with profound implications for human health.
INT vs. Resazurin: A Modern Comparison of Viability Assays for Accurate Bacterial MIC Determination
This article provides a comprehensive, evidence-based comparison of the tetrazolium salt INT (2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride) and the oxidation-reduction indicator resazurin for assessing bacterial viability in Minimum Inhibitory Concentration (MIC) assays.
Validating INT Colorimetric Assay Against Broth Microdilution: A Comprehensive Guide for MIC Determination in Antimicrobial Research
This article provides a detailed methodological and analytical framework for researchers validating the INT (2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride) colorimetric assay against the reference broth microdilution (BMD) method for Minimum Inhibitory Concentration (MIC)...
INT Colorimetric Assay: A Complete Guide to MIC Determination for Antimicrobial Testing
This comprehensive article explores the INT colorimetric assay for Minimum Inhibitory Concentration (MIC) determination, a vital technique in antimicrobial research and drug development.
INT Colorimetric Assay: A Practical Guide for Determining MIC and MBC of Pleurotus opuntiae Extracts
This comprehensive guide details the application of the INT (2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride) colorimetric assay for evaluating the antibacterial efficacy of Pleurotus opuntiae extracts.
INT Assay for Drug-Resistant TB: Performance, Optimization, and Future Applications in Research
This article provides a comprehensive analysis of the INT assay's performance in detecting drug-resistant Mycobacterium tuberculosis (MTB).
Colored Antimicrobials and INT Assay Interference: Challenges, Solutions, and Best Practices for Accurate Microbial Viability Testing
This comprehensive article addresses a critical challenge in microbiology and drug discovery: the interference of colored antimicrobial compounds with the widely used INT (2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride) viability assay.