Research Articles
INT Colorimetric Assay for MIC Determination: A Comprehensive Guide from Principle to Precision
This article provides a thorough exploration of the p-iodonitrophenyltetrazolium violet (INT) colorimetric assay for determining the Minimum Inhibitory Concentration (MIC) of antimicrobial agents.
Therapeutic Drug Monitoring of Narrow Therapeutic Index Antibiotics: Protocols for Precision Dosing in Critical Care and Drug Development
This article provides a comprehensive resource for researchers, scientists, and drug development professionals on therapeutic drug monitoring (TDM) protocols for narrow therapeutic index (NTI) antibiotics.
Population Pharmacokinetic Modeling for Anti-infective Dose Optimization: A Comprehensive Guide for Researchers
This article provides a comprehensive overview of population pharmacokinetic (PopPK) modeling and its critical application in optimizing anti-infective therapy, particularly in challenging patient populations like the critically ill.
Agar Well Diffusion Method: A Complete Guide to Antimicrobial Activity Screening
This article provides a comprehensive guide to the agar well diffusion method, a cornerstone technique for in vitro antimicrobial activity screening.
Horizontal Gene Transfer: Unveiling the Mechanisms Driving the Spread of Antibiotic Resistance
This article provides a comprehensive analysis of the mechanisms, dynamics, and control of transferable antibiotic resistance genes (ARGs), a primary driver of the global antimicrobial resistance crisis.
Optimizing Antibacterial Production with Response Surface Methodology: A Comprehensive Guide for Biomedical Research
This article provides a comprehensive guide on applying Response Surface Methodology (RSM) to optimize the production of antibacterials, such as bacteriocins and novel metabolites, from microbial sources.
Analyzing the 2024 WHO Priority Pathogen Lists: A Strategic Guide for AMR Research and Pandemic Preparedness
This analysis provides researchers, scientists, and drug development professionals with a comprehensive examination of the World Health Organization's updated 2024 pathogen lists.
Optimizing Novel Anti-Infective Agents: A PK/PD and Pharmacometric Framework for Modern Drug Development
This article provides a comprehensive analysis of the pharmacokinetic (PK) and pharmacodynamic (PD) properties underpinning the development of novel anti-infective agents.
Antimicrobial Peptides from Lactiplantibacillus plantarum: Discovery, Mechanisms, and Biotechnological Applications in Drug Development
This article provides a comprehensive resource for researchers and drug development professionals on the diverse arsenal of antimicrobial peptides (AMPs) produced by Lactiplantibacillus plantarum.
Bioactive Mycoconstituents of Pleurotus opuntiae: A Novel Frontier in Combating Antimicrobial Resistance
This article comprehensively explores the antimicrobial potential of Pleurotus opuntiae, an underexplored medicinal mushroom.