Research Articles
Decoding Klebsiella pneumoniae: Advanced Methods for Tracking Mobile Genetic Elements and Antimicrobial Resistance
This article provides a comprehensive guide for researchers and drug development professionals on the critical role of mobile genetic elements (MGEs) in driving antimicrobial resistance (AMR) and virulence in Klebsiella...
TLC-Bioautography: A Powerful Guide for Isolating and Identifying Antimicrobial Compounds in Natural Products and Drug Discovery
This comprehensive guide details TLC-bioautography, a key hyphenated technique for tracking antimicrobial activity directly on chromatographic plates.
TGV-49: A Novel Antibiotic's Promise Against Multidrug-Resistant Gram-Negative Pathogens
The escalating crisis of antimicrobial resistance (AMR), particularly among Gram-negative pathogens like Pseudomonas aeruginosa, Acinetobacter baumannii, and Enterobacterales, necessitates urgent innovation.
Navigating Pharmacokinetic Complexity: A Comprehensive Guide to TDM Protocol Optimization in Obese Patients
This article provides a critical review and framework for optimizing Therapeutic Drug Monitoring (TDM) protocols in obese patient populations.
Therapeutic Drug Monitoring (TDM) for Dalbavancin and Oritavancin: A Comprehensive Protocol Guide for Researchers and Drug Developers
This article provides a detailed, research-oriented analysis of Therapeutic Drug Monitoring (TDM) protocols for the novel long-acting lipoglycopeptides dalbavancin and oritavancin.
TDM Protocol Development for Anti-MRSA Antibiotics: A Comprehensive Guide for Precision Dosing in Drug Development
This article provides a detailed, current overview of Therapeutic Drug Monitoring (TDM) protocol development for anti-MRSA (Methicillin-resistant Staphylococcus aureus) antibiotics.
Precision Dosing in Pneumonia: Optimizing Anti-MRSA Therapy with Therapeutic Drug Monitoring (TDM)
This article provides a comprehensive examination of Therapeutic Drug Monitoring (TDM) for anti-MRSA agents in pneumonia treatment, targeted at researchers and drug development professionals.
Antibiotic TDM Efficacy Review: Comparative Analysis of Beta-Lactams, Aminoglycosides, Glycopeptides, and Newer Agents
This article provides a comprehensive comparative analysis of therapeutic drug monitoring (TDM) efficacy across major antibiotic classes, including beta-lactams, aminoglycosides, glycopeptides, and newer agents.
Beyond MICs: A Comprehensive Cost-Effectiveness Analysis of TDM in Antimicrobial Stewardship Programs
Therapeutic Drug Monitoring (TDM) is emerging as a cornerstone of precision antimicrobial stewardship (AMS), but its economic justification remains a critical hurdle for widespread implementation.
Efflux Pump Inhibitors: Cutting-Edge Strategies to Overcome Antimicrobial Resistance in Drug Development
This article provides a comprehensive analysis of strategies to counteract efflux pump-mediated antimicrobial resistance (AMR), a critical barrier in modern therapeutics.